1. Co-workers and bosses are not usually your friends: You will spend a lot of time with co-workers. You may eventually become close friends with some of them, but in general, you will move on in three years and aside from maintaining cordial relations you will not go out of your way to invite them over to dinner. They will treat you in exactly the same way. You should be a good person to everyone you meet — it is the moral thing to do, and as a sidenote will really help your networking — but do not be under the delusion that everyone is your friend.
2. Academia is not like the real world: Your professors might understand how the academic job market works (short story: it is ridiculously inefficient in engineering and fubared beyond mortal comprehension in English) but they often have quixotic understandings of how the real world works. For example, they may push you to get extra degrees because a) it sounds like a good idea to them and b) they enjoy having research-producing peons who work for ramen. Remember, market wages for people capable of producing research are $80~100k+++ in your field. That buys an awful lot of ramen.
3. At the end of the day, your life happiness will not be dominated by your career. Either talk to older people or trust the social scientists who have: family, faith, hobbies, etc etc generally swamp career achievements and money in terms of things which actually produce happiness. Optimize appropriately. Your career is important, and right now it might seem like the most important thing in your life, but odds are that is not what you’ll believe forever. Work to live, don’t live to work.